Sunday, September 18, 2016

New mosquito-borne disease detected in Haiti

Date: September 15, 2016

Source:UF Health


Researchers have identified a patient in Haiti with a serious mosquito-borne illness that has never before been reported in the Caribbean nation.


John Lednicky, Ph.D.
Credit: Image courtesy of UF Health

University of Florida researchers have identified a patient in Haiti with a serious mosquito-borne illness that has never before been reported in the Caribbean nation.

Known as "Mayaro virus," it is closely related to chikungunya virus and was first isolated in Trinidad in 1954. Most reported cases, however, have been confined to small outbreaks in the Amazon. Whether this case signals the start of a new outbreak in the Caribbean region is currently unknown.

"While current attention has been focused on the Zika virus, the finding of yet another mosquito-borne virus which may be starting to circulate in the Caribbean is of concern," said Glenn Morris, M.D., M.P.H., director of the UF Emerging Pathogens Institute. "Hopefully we will not see the same massive epidemics that we saw with chikungunya, dengue and now Zika. However, these findings underscore the fact that there are additional viruses 'waiting in the wings' that may pose threats in the future, and for which we need to be watching."

The case was identified from a blood sample taken in January 2015 from an 8-year-old boy in rural Haiti. The patient had a fever and abdominal pain but no rash or conjunctivitis. Because faculty from the UF Emerging Pathogens Institute were in the region during and after the 2014 chikungunya outbreak, plasma samples were obtained from febrile children and analyzed for the presence of chikungunya virus RNA using a genetic identification technique known as reverse transcription polymerase chain reaction.

The plasma samples, which were examined by UF's Maha Elbadry, Ph.D., in Gressier, Haiti, were then sent to EPI for additional virology and molecular analyses, focusing on the detection of chikungunya, dengue and Zika viruses. Dengue virus was detected in the patient, in addition to a "new" virus that was subsequently identified as Mayaro.

"The virus we detected is genetically different from the ones that have been described recently in Brazil, and we don't know yet if it is unique to Haiti or if it is a recombinant strain from different types of Mayaro viruses," said John Lednicky, Ph.D., an associate professor in the environmental and global health department at the UF College of Public Health and Health Professions and the study's lead author.

The findings were published online Aug. 26 in the Centers for Disease Control and Prevention's journal Emerging Infectious Diseases.

The symptoms of Mayaro fever are similar to those of chikungunya fever: fever, joint pain, muscle pain and rashes. Abdominal pain is also a feature of Mayaro fever, however, and joint pain can last longer.

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The above post is reprinted from materials provided by UF Health. The original item was written by Evan Barton. Note: Content may be edited for style and length.

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